AAO: Diabetic Retinopathy Usually No Worse With Semaglutide in T2D

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

THURSDAY, Nov. 9, 2023 -- For patients with type 2 diabetes mellitus, most eyes have no worsening of diabetic retinopathy (DR) after initiation of semaglutide, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Nov. 3 to 6 in San Francisco.

Zeeshan Haq, M.D., from Retina Consultants of Minnesota in Minneapolis, and colleagues examined changes in DR status after semaglutide initiation in a retrospective case series involving patients with type 2 diabetes mellitus who initiated semaglutide between January 2013 and December 2021. A total of 96,432 eyes were included.

The researchers found that at baseline, 71.8, 18.4, and 9.8 percent of eyes had no or background DR, mild or moderate nonproliferative DR (NPDR), and severe NPDR or proliferative DR (PDR), respectively. At three, six, 12, and 24 months, 1.3, 1.2, 1.6, and 2.2 percent of eyes with no or background DR, respectively, had a worsening in their status; the corresponding proportions were 2.4, 3.0, 3.4, and 3.5 percent among eyes with mild or moderate NPDR. Improvement in DR status was recorded in 40.0, 37.8, 47.7, and 58.7 percent of eyes with severe NPDR or PDR at three, six, 12, and 24 months, respectively.

"The impact of semaglutide initiation on short- and long-term outcomes in potentially high-risk patients, such as those with severe nonproliferative or proliferative diabetic retinopathy, should be investigated further," Haq said in a statement. "Ultimately, diabetic patients who are considering semaglutide should consult with their primary and eye care providers regarding their individual situation."

Press Release

More Information

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2023-11-10 01:09

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords