Antiobesity Medications Tied to Decreased Alcohol Use

Follow Drugslib on

Medically reviewed by Carmen Pope, BPharm. Last updated on Dec 3, 2024.

By Lori Solomon HealthDay Reporter

TUESDAY, Dec. 3, 2024 -- Nearly half of participants in a weight loss program who initiated an antiobesity medication and who consumed alcohol at baseline reported decreases in their alcohol use, according to a research letter published online Nov. 26 in JAMA Network Open.

Lisa R. Miller-Matero, Ph.D., from Henry Ford Health in Detroit, and colleagues examined changes in alcohol use among 14,053 individuals enrolled in a telehealth weight management program after initiation of an antiobesity medication (first- or second-generation glucagon-like peptide-1 receptor agonists; January 2022 to August 2023). Most participants (86.2 percent) were prescribed a second-generation medication.

The researchers found that approximately half of participants reported drinking any alcohol at baseline (53.3 percent), and across all participants, 24.2 percent had a decrease in alcohol use. For the 7,491 participants with alcohol use at baseline, 45.3 percent reported decreasing a category of alcohol use, 52.4 percent reported no change, and 2.3 percent reported an increase. Further, among participants who reported alcohol use at baseline, those with a higher class of obesity and those with higher levels of drinking were more likely to lessen their use. Greater decreases in alcohol use were seen among individuals receiving bupropion and naltrexone compared with metformin. However, when controlling for weight loss, this association was no longer significant.

"Future research would benefit from a randomized trial comparing antiobesity medications with a placebo-controlled or nonpharmacological weight management group," the authors write.

Several authors reported ties to WW International.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-12-04 06:00

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords