Bidirectional Link Seen for Rheumatoid Arthritis, Interstitial Lung Disease
By Elana Gotkine HealthDay Reporter
TUESDAY, Nov. 5, 2024 -- There is a bidirectional association for rheumatoid arthritis (RA) and interstitial lung disease (ILD), according to a study published online Oct. 12 in the Journal of Clinical Medicine.
Bo-Guen Kim, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the bidirectional relationship between RA and ILD using Mendelian randomization (MR) analyses. Data were obtained from 474,450 participants of European ancestry and 351,653 participants of East Asian ancestry.
The researchers found significant evidence of an increased risk for ILD associated with RA among individuals of European and East Asian ancestries (odds ratios [95 percent confidence intervals], 1.08 [1.03 to 1.14; P = 0.003] and 1.37 [1.23 to 1.54; P < 0.001], respectively) in the primary analysis. The reverse MR showed significant evidence of an increased risk for RA associated with ILD among those of European ancestry (odds ratio, 1.12; 95 percent confidence interval, 1.05 to 1.19; P < 0.001), but no increased risk was seen for those of East Asian ancestry (odds ratio, 1.02; 95 percent confidence interval, 0.91 to 1.14; P = 0.740).
"As our findings only present the results for genetic predisposition, the shared pathogenesis between the two diseases indicates the importance of further studies incorporating other factors that may impact the natural course of either disease," the authors write.
Several authors disclosed financial ties to Basgenbio.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
Source: HealthDay
Posted : 2024-11-06 06:00
Read more
- Parents or Ambulance: How a Child Reaches an ER Could Matter
- FDA Appoints New Head of Medical Devices
- Poll Finds Most Americans Stressed Over Election, Future of Nation
- AI Might Help Pick Up Heart Trouble in Dogs
- American Society for Radiation Oncology, Sept. 29-Oct. 2
- Exercise Cuts Dependence in Those With Alcohol Use Disorder
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions