COVID-19 Linked to More Severe Outcomes Than Flu, RSV in 2022-2023 Season

Medically reviewed by Carmen Pope, BPharm. Last updated on Jan 30, 2025.

By Elana Gotkine HealthDay Reporter

THURSDAY, Jan. 30, 2025 -- COVID-19 was associated with more severe disease outcomes than influenza or respiratory syncytial virus (RSV) during the 2022 to 2023 season, according to a study published online Jan. 27 in JAMA Internal Medicine.

Kristina L. Bajema, M.D., from Veterans Affairs Portland Health Care System in Oregon, and colleagues compared disease severity of COVID-19, influenza, and RSV among U.S. veterans in a retrospective cohort study. The cumulative incidence and risk differences were calculated for the primary outcomes of 30-day hospitalization, intensive care unit admission, and death.

The researchers found that the 30-day risk for hospitalization was similar for COVID-19 and influenza (16.2 versus 16.3 percent) and was lower for RSV (14.3 percent) during the 2023 to 2024 season. The 30-day risk for death was slightly higher for COVID-19 compared with influenza or RSV during the 2022 to 2023 season (1.0 percent versus 0.7 and 0.7 percent), but was similar during the 2023 to 2024 season. At 180 days, mortality risk was higher for COVID-19 during both seasons. In both seasons, higher mortality was seen for veterans without COVID-19 vaccination in the previous year compared with those without seasonal influenza vaccination. In contrast, no mortality differences were seen at any time point between COVID-19 and influenza among those vaccinated against their respective infections.

"Severe acute respiratory syndrome coronavirus 2 was far more common than influenza or RSV and resulted in more severe disease outcomes, including short-term hospitalization and mortality through six months," the authors write. "This was most apparent among older adults and attenuated by updated COVID-19 vaccination."

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords