COVID-19 Vaccination Not Tied to Adverse Pregnancy Outcomes

Follow Drugslib on

Medically reviewed by Drugs.com.

By Lori Solomon HealthDay Reporter

TUESDAY, June 25, 2024 -- mRNA COVID-19 vaccination during pregnancy is not associated with an increased risk of adverse pregnancy outcomes, according to a study published in the June issue of Obstetrics & Gynecology.

Kimberly K. Vesco, M.D., M.P.H., from Kaiser Permanente Center for Health Research in Portland, Oregon, and colleagues evaluated the association between antenatal mRNA COVID-19 vaccination and risk of adverse pregnancy outcomes. Analysis included 55,591 individuals with singleton pregnancies with live deliveries (June 1, 2021, to Jan. 31, 2022), with data available from eight integrated health care systems participating in the Vaccine Safety Datalink.

The researchers found that 42.3 percent of the cohort received one or two mRNA COVID-19 vaccine doses during pregnancy, with receipt varying by maternal age, race, Hispanic ethnicity, and history of COVID-19. mRNA COVID-19 vaccination was associated with a decreased risk of preterm birth (adjusted hazard ratio [aHR], 0.89; 95 percent confidence interval [CI], 0.83 to 0.94) compared with no vaccination. There was no association between vaccination and small for gestational age (aHR, 1.06; 95 percent CI, 0.99 to 1.13), gestational diabetes (adjusted risk ratio [aRR], 1.00; 95 percent CI, 0.90 to 1.10), gestational hypertension (aRR, 1.08; 95 percent CI, 0.96 to 1.22), or preeclampsia-eclampsia-HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome (aRR, 1.10; 95 percent CI, 0.97 to 1.24).

"This information will be helpful for patients and clinicians when considering COVID-19 vaccination in pregnancy," the authors write.

Several authors disclosed ties to the pharmaceutical industry.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-06-26 01:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords