Exposure to Glucocorticoids Increases Risk for New-Onset Diabetes

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

WEDNESDAY, Sept. 11, 2024 -- Exposure to systemic glucocorticoids during hospitalization is associated with an increased risk for new-onset diabetes, according to a study presented at the annual of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.

Rajna Golubic, M.D., Ph.D., from the University of Oxford in the United Kingdom, and colleagues estimated the crude and age- and sex-adjusted incidence rate ratio (IRR) of new-onset diabetes arising during time exposed versus unexposed to systematic glucocorticoids. The analysis data set included 451,606 adults free from diabetes (median age, 52 years).

The researchers found that autoimmune/inflammatory diseases/infections were the most common indication for systemic glucocorticoids (65.3 percent). Overall, 1.8 and 0.8 percent of ever-exposed versus never-exposed individuals developed new-onset diabetes in the exposed and nonexposed time in years. The incidence rates were 51.9 and 18.5 per 100 person-years for the ever-exposed and never-exposed groups, respectively. The median length of stay in days was three and one for ever-exposed and never-exposed participants. For new-onset diabetes associated with glucocorticoids, the unadjusted and age- and sex-adjusted IRRs were 2.8 and 2.6, respectively.

"These latest results give clinical staff a better estimate of how likely new diabetes is to occur and could prompt doctors to plan clinical care more effectively to detect and manage new diabetes," Golubic said in a statement.

Abstract

More Information

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-09-12 08:59

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords