Filtration of Traffic-Related Air Pollution Mitigates Its Impact on BP

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

MONDAY, Nov. 27, 2023 -- Filtration of traffic-related air pollution (TRAP) may mitigate its adverse effects on blood pressure, according to a study published online Nov. 28 in the Annals of Internal Medicine.

Michael T. Young, M.P.H., Ph.D., from the University of Washington in Seattle, and colleagues conducted a randomized crossover trial involving in-vehicle scripted commutes driven through traffic in Seattle among 16 normotensive persons aged 22 to 45 years (mean age, 29.7 years). On-road air was entrained into the vehicle on two days; the vehicle was equipped with high-efficiency particulate air (HEPA) filtration on another day. Before, during, and up to 24 hours after a drive, 14 three-minute periods of blood pressure were recorded.

Predrive blood pressure was 122.7/70.8 mm Hg; drive duration was 122.3 minutes. The researchers found that among 13 participants with complete data, mean diastolic blood pressure at one hour was 4.7 mm Hg higher for unfiltered drives versus filtered drives, adjusting for predrive levels, order, and carryover; mean adjusted systolic blood pressure was 4.5 mm Hg higher. At 24 hours, adjusted mean diastolic and systolic blood pressure were 3.8 and 1.1 mm Hg higher, respectively, for unfiltered drives. In unfiltered drives, the adjusted mean image-based central retinal arteriolar equivalent was 2.7 µm wider.

"Our study reinforces existing literature suggesting that traffic-derived particulate matter may be implicated in hypertension," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2023-11-28 08:32

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords