Home-Based Exercise, Coaching Improves Fitness in Neuromuscular Diseases

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

WEDNESDAY, June 4, 2025 -- Combined personalized home-based aerobic exercise and coaching improves physical fitness for people with neuromuscular diseases, according to a study published online June 4 in Neurology.

Sander Oorschot, from the University of Amsterdam, and colleagues examined the efficacy of combined personalized home-based aerobic exercise and coaching on physical fitness in people with neuromuscular diseases in a multicenter, assessor-blinded, randomized controlled trial. Participants with different types of neuromuscular diseases were randomly allocated to a six-month intervention or usual care (44 and 47 participants, respectively). Assessments were performed at baseline and at six and 12 months postintervention.

The researchers found that the mean group difference in physical fitness, measured as peak oxygen uptake, was 2.2 and 1.7 mL/min/kg directly after intervention and on average over time, respectively, in favor of the intervention group. In the secondary outcomes, including daily physical activity, quality of life, physical functioning, metabolic syndrome markers, and creatine kinase level, no significant between-group differences were seen. There were 25 and 22 adverse events reported in the intervention and usual care groups, respectively. No changes were seen in creatine kinase levels.

"Future research should look at how changes in fitness levels affect how well people with neuromuscular diseases can do everyday activities," coauthor Eric L. Voorn, Ph.D., also from the University of Amsterdam, said in a statement. "It should also look at ways to motivate people to keep exercising regularly in their daily lives to make sure the benefits of long-term treatments are maintained."

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2025-06-05 12:00

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords