Intermittent Fasting Aids Early Diabetes Outcomes More Than Drugs

Follow Drugslib on

Medically reviewed by Carmen Pope, BPharm. Last updated on June 25, 2024.

By Lori Solomon HealthDay Reporter

TUESDAY, June 25, 2024 -- Intermittent fasting may be a more effective intervention than drugs for people with early diabetes and either obesity or overweight, according to a study published online June 21 in JAMA Network Open.

Lixin Guo, M.D., from the Chinese Academy of Medical Sciences in Beijing, and colleagues evaluated the effect of intermittent fasting (two nonconsecutive fasting days and five days of habitual intake per week and meal replacement diet (5:2 MR) on glycemic control among patients with early type 2 diabetes compared to metformin and empagliflozin for 16 weeks. Analysis included 405 individuals with overweight or obesity randomly assigned to the groups (1:1:1).

The researchers found that from baseline to week 16, participants in the 5:2 MR group showed the greatest reduction in HbA1c (least-squares mean [LSM], −1.9 percent), which was significantly greater than patients receiving metformin (adjusted LSM difference, −0.3 percent) and empagliflozin (adjusted LSM difference, −0.4 percent). The mean weight loss in the 5:2 MR group (LSM, −9.7 kg) was also greater at week 16 than the metformin (LSM, −5.5 kg) and empagliflozin (LSM, −5.8 kg) groups.

"The 5:2 MR approach may serve as an effective initial lifestyle intervention instead of antidiabetic drugs for patients with type 2 diabetes," the authors write.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-06-26 03:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords