Lower Levels of Total Cholesterol Seen in More Recent Birth Cohorts

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

FRIDAY, Dec. 6, 2024 -- More recent birth cohorts have lower levels of total cholesterol and fasting triglyceride levels, and higher levels of fasting glucose, according to a study published online Dec. 6 in JAMA Network Open.

Xiaoning Huang, Ph.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues quantified national trends in total cholesterol, fasting triglyceride, and fasting glucose levels among cohorts born between 1920 and 1999 to examine the association of these patterns with body mass index (BMI) using data from the National Health and Nutrition Examination Survey 1999-2000 to 2017-2020 cycles.

Data were included for 52,006 participants, weighted to represent 264,664,915 U.S. adults. The researchers found that the mean difference per one-decade younger birth cohort was −7.1, −13.1, and 2.7 mg/dL for total cholesterol level, fasting triglyceride level, and fasting glucose level, respectively, for the 50th percentile of measures. The associations between birth cohort and lipid levels were attenuated by BMI, while the association with fasting glucose levels was enhanced by BMI. However, of the associations between birth cohorts and cardiometabolic outcomes, up to 80 percent were not mediated through BMI.

"While the mean lipid profile in younger generations was improved compared with older generations, this improvement hinges on an ongoing push to continue to educate the public and health care professionals about modifying risk even at a young age," the authors write.

One author disclosed ties to Omron Healthcare and Ciconia Medical.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-12-08 00:00

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords