Multimodal Intervention Does Not Cut Opioid Overdose Deaths

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

TUESDAY, June 18, 2024 -- A multimodal intervention trial implementing evidence-based practice strategies does not reduce opioid overdose deaths, according to a study published online June 16 in the New England Journal of Medicine to coincide with the annual scientific meeting of the College on Problems of Drug Dependence, held from June 16 to 19 in Montreal.

Jeffrey H. Samet, M.D., M.P.H., from Boston Medical Center, and colleagues randomly assigned 67 communities in Kentucky, Massachusetts, New York, and Ohio to receive a community-engaged intervention to reduce opioid-related overdose deaths or wait-list control (34 and 33 communities, respectively).

The researchers found that the population-averaged rates of opioid-related overdose deaths were similar in the intervention and control groups during the comparison period from July 2021 through June 2022 (47.2 versus 51.7 deaths per 100,000 population), for an adjusted rate ratio of 0.91 (95 percent confidence interval, 0.76 to 1.09; P = 0.30). There was no appreciable difference noted in the effect of the intervention on the rate of opioid-related overdose deaths according to state, urban or rural category, age, sex, or race or ethnic group. Intervention communities implemented 615 of 806 evidence-based practice strategies selected by communities.

"Although there were no significant between-group differences in the rate of opioid-related overdose deaths, the trial showed that the Communities That Heal community-engaged intervention, with its leveraging of community coalitions and a data-driven approach, can bring about meaningful progress in implementing evidence-based practices," the authors write.

Several authors disclosed ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

More Information

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-06-19 07:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords