Odds of IBS, Functional Dyspepsia Increased After Acute Gastroenteritis Episode

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

WEDNESDAY, July 17, 2024 -- A considerable proportion of individuals experiencing acute gastroenteritis develop postinfection irritable bowel syndrome (PI-IBS) and postinfection functional dyspepsia (PI-FD), according to a review published online July 16 in Gut.

Serena Porcari, M.D., from Università Cattolica del Sacro Cuore in Rome, and colleagues conducted a systematic review and meta-analysis to examine the prevalence of PI-IBS or PI-FD after acute gastroenteritis using data from observational studies recruiting 50 or more adults. Forty-seven studies were eligible, with 28,170 individuals.

The researchers found that the overall prevalence of PI-IBS was 14.5 percent and the prevalence of PI-FD was 12.7 percent. In 39.8 percent of individuals, IBS persisted in the long term (greater than five years of follow-up) after diagnosis. Compared with nonexposed controls, individuals experiencing acute gastroenteritis had significantly higher odds of IBS and FD (odds ratios, 4.3 and 3.0, respectively). The strongest association was seen for PI-IBS with parasites (prevalence, 30.1 percent), but only in two studies, followed by bacteria and viruses (18.3 and 10.7 percent). The highest PI-IBS prevalence was seen in association with Campylobacter in available studies (20.7 percent), while the highest odds for PI-IBS were yielded by Proteobacteria and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; odds ratio, 5.4 for each). The prevalence of PI-FD was 10.0 and 13.6 percent for SARS-CoV-2 and bacteria (Enterobacteriaceae, 19.4 percent), respectively.

"Our findings provide an update to the epidemiology of PI-IBS and PI-FD and of the likelihood of developing them after acute gastroenteritis," the authors write.

Several authors disclosed ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-07-18 01:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords