One-Dose HPV Vaccination Averts Similar Number of Cancers as Two Doses

Follow Drugslib on

Medically reviewed by Carmen Pope, BPharm. Last updated on Oct 7, 2024.

By Elana Gotkine HealthDay Reporter

MONDAY, Oct. 7, 2024 -- A one-dose human papillomavirus (HPV) vaccination program is projected to prevent a similar number of cervical cancers as a two-dose program, according to a study published online Oct. 7 in CMAJ, the journal of the Canadian Medical Association.

Mélanie Drolet, Ph.D., from the Université Laval in Québec City, and colleagues used an individual-based transmission-dynamic model of HPV infections and diseases to mathematically model vaccination programs in two provinces: Quebec, with around 85 percent vaccination coverage, and Ontario, with around 65 percent coverage. The authors sought to project the population-level impact and efficiency of switching from two- to one-dose, gender-neutral, routine HPV vaccination.

The researchers projected that under various scenarios, one-dose HPV vaccination would avert a similar number of cervical cancers as two doses in Canada. Under the most pessimistic scenario (vaccine duration, 25 years), one dose would avert fewer cervical cancer cases than two doses, with a difference of about 3 percentage points over 100 years. Elimination of cervical cancer was projected with all one-dose scenarios (fewer than four cervical cancers/100,000 female-years), and one dose was considered to be a substantially more efficient use of vaccine doses than two doses.

"One-dose vaccination represents a more efficient use of vaccine doses and is projected to lead to elimination of cervical cancer in Canada," the authors write. "Continued monitoring of one-dose protection over time is required to rapidly detect any signs of waning one-dose efficacy."

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-10-08 06:00

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords