Phthalate Chemicals Tied to Costly Preterm Births in the United States
By Lori Solomon HealthDay Reporter
FRIDAY, Feb. 9, 2024 -- Hormone disruptor phthalate chemicals were associated with nearly 56,600 preterm births in the United States in 2018, according to a study published online Feb. 6 in The Lancet Planetary Health.
Leonardo Trasande, M.D., from the New York University Grossman School of Medicine in New York City, and colleagues examined associations between 20 phthalate metabolites and birth weight and gestational age. The analysis included data from 5,006 mother-child dyads participating in the U.S. National Institutes of Health Environmental Influences on Child Health Outcomes Program (1998 to 2022).
The researchers found that phthalic acid, diisodecyl phthalate (DiDP), di-n-octyl phthalate (DnOP), and diisononyl phthalate (DiNP) were most strongly associated with gestational age, birth length, and birth weight compared with di-2-ethylhexyl phthalate (DEHP) or other metabolite groupings. While DEHP was associated with preterm birth (odds ratio [OR], 1.45), the risks per log10 increase were higher for phthalic acid (OR, 2.71), DiNP (OR, 2.25), DiDP (OR, 1.69), and DnOP (OR, 2.90). An estimated 56,595 phthalate-attributable preterm birth cases occurred in 2018 with associated costs of US$3.84 billion.
"We identified associations of phthalate exposure with decreased gestational age in a large and diverse sample generally representative of the USA," the authors write. "This finding suggests the adverse consequences of substitution of DEHP with chemically similar phthalates and need to regulate chemicals with similar properties as a class."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
Source: HealthDay
Posted : 2024-02-10 02:15
Read more

- GLP-1 Receptor Agonist Use Linked to Nonarteritic Anterior Ischemic Optic Neuropathy
- Adding Anxiety as Qualifier for Medical Cannabis Increases Number of Certifications
- Cardiac Arrest Can Happen Suddenly — Here's Everything You Need to Know
- Sobi Announces U.S. Food and Drug Administration Approves Doptelet (avatrombopag) for the Treatment of Thrombocytopenia in Pediatric Patients One Year and Older with Persistent or Chronic Immune Thrombocytopenia (ITP)
- Hispanic People Have Unexplained Higher Risk For Nerve Disorder
- Scientists Find New Ecosystem in Deepest Trenches of Pacific Ocean
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions