Postoperative A-Fib Tied to Worse Outcomes After Valve Surgery

Follow Drugslib on

Medically reviewed by Drugs.com.

By Lori Solomon HealthDay Reporter

FRIDAY, Dec. 15, 2023 -- Postoperative atrial fibrillation (POAF) is associated with an increased rate of neurologic events and worse long-term survival, according to a study published online Sept. 11 in the Journal of Thoracic and Cardiovascular Surgery.

Whitney Fu, M.D., from the University of Michigan in Ann Arbor, and colleagues examined the rate of POAF, incidence of neurologic events, development of permanent atrial fibrillation, and mortality in patients undergoing isolated mitral valve surgery. Analysis included 922 adult patients from 2011 to 2022 with no preoperative history of arrhythmias.

The researchers found that over a median follow-up of 4.9 months, the incidence of POAF was 39 percent. Risk factors for POAF included diabetes (odds ratio [OR], 2.2; 95 percent confidence interval [CI], 1.2 to 4.1; P = 0.01) and increasing age (OR, 1.1; 95 percent CI, 1.0 to 1.1; P < 0.001). New York Heart Association functional class was not a risk factor. There was an association between POAF and development of permanent atrial fibrillation (OR, 3.2; 95 percent CI, 1.9 to 5.4; P < 0.001), which was associated with increased risk of neurologic events (OR, 3.8; 95 percent CI, 1.5 to 9.7; P = 0.004). Patients with POAF had worse unadjusted and adjusted long-term mortality (hazard ratio, 1.8; 95 percent CI, 1.1 to 3.1; P = 0.03).

"POAF is not benign and carries a long-term mortality implication," the authors write.

Several authors disclosed ties to the medical technology industry.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2023-12-16 02:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords