Rapid Weight Loss Beats Slow and Steady in New Clinical Trial

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By HealthDay Staff HealthDay Reporter

Medically reviewed by Drugs.com

via HealthDay

MONDAY, May 18, 2026 — When it comes to weight loss, is slow and steady really the winning strategy? Or could a rapid drop actually lead to better long-term results?

New research presented in Istanbul last week at the European Congress on Obesity is challenging the long-held belief that losing weight too quickly leads to rebound weight gain.

In this 52-week randomized clinical trial, researchers followed 284 adults with obesity who were assigned to either a rapid or gradual weight-loss program.

During the first 16 weeks, the rapid weight-loss group followed a structured low-calorie plan starting at under 1,000 calories per day, increasing step-by-step to about 1,500 calories daily. The gradual group reduced intake more moderately, averaging around 1,400 calories per day.

After that, both groups entered the same 36-week weight-regain prevention program with coaching and ongoing support.

The result?

Those in the rapid weight-loss group lost nearly 13% of their body weight in the first 16 weeks, compared to just over 8% in the gradual group.

A year later, they still maintained significantly greater weight loss overall and were much more likely to hit clinically meaningful targets linked to lower risks of type 2 diabetes, high blood pressure, heart disease and osteoarthritis.

"Our results clearly challenge the prevailing belief that slow and steady gradual weight loss is necessary to prevent weight regain and reduce obesity-related complications," said Line Kristin Johnson, of the Vestfold Hospital Trust in Tønsberg, Norway.

She said the urgent need for weight-loss and weight-maintenance strategies make the findings particularly relevant.

"As many individuals with obesity cannot access or afford medical or surgical treatments, our results support the potential of effective, commercially available weight-reduction programs to help reduce the growing burden on public healthcare systems," she said in a news release.

Research presented at meetings is typically considered preliminary until published in a peer-reviewed journal.

Sources

  • HealthDay TV, May 18, 2026

    • Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

    Source: HealthDay

    Posted : 2026-05-18 22:21

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