Risk for Sudden Unexpected Infant Death Increased With Maternal Obesity

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

WEDNESDAY, July 31, 2024 -- Infants born to mothers with obesity have an increased risk for sudden unexpected infant death (SUID), according to a study published online July 29 in JAMA Pediatrics.

Darren Tanner, Ph.D., from the AI for Good Research Lab at Microsoft Corporation in Redmond, Washington, and colleagues examined whether maternal obesity is a risk factor for SUID in a U.S. nationwide cohort study using U.S. Centers for Disease Control and Prevention National Center for Health Statistics linked birth-infant death records for birth cohorts in 2015 through 2019. Of 18,857,694 live births eligible for analysis, 16,545 died of SUID (rate, 0.88 per 1,000 live births).

The researchers found that compared with mothers with normal body mass index (BMI, 18 to 24.9 kg/m2), infants born to mothers with obesity had a higher SUID risk after confounder adjustment, which increased with increasing obesity severity. The risks increased for infants of mothers with class I, class II, and class III obesity (adjusted odds ratios, 1.10, 1.20, and 1.39, respectively). Increased BMI was monotonically associated with increased SUID risk in a generalized additive model, with an acceleration of the risk for BMIs greater than about 25 to 30 kg/m2. Overall, about 5.4 percent of SUID cases could be attributed to maternal obesity.

"As the obesity epidemic in the United States and around the world continues to accelerate, maternal obesity is likely to play an increasingly larger role in SUID prevalence over time," the authors write. "As our findings are observational, future work is needed to elucidate the specific causal mechanisms for the obesity-SUID association."

Abstract/Full Text

Editorial (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-08-01 01:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords