Short Sleep Duration Impairs Insulin Sensitivity in Women

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

FRIDAY, Nov. 17, 2023 -- Short sleep duration for six weeks impairs insulin sensitivity in women, according to a study published online Nov. 15 in Diabetes Care.

Faris M. Zuraikat, Ph.D., from the Columbia University Irving Medical Center in New York City, and colleagues examined whether prolonged mild sleep restriction (SR), resembling real-world short sleep, impaired glucose metabolism in 36 women (11 postmenopausal), aged 20 to 75 years, without cardiometabolic diseases, with total sleep time of seven to nine hours/night in a randomized crossover study. The study included two six-week phases: maintenance of adequate sleep (AS) and 1.5 hours/night SR.

The researchers found that total sleep time was reduced by 1.34 ± 0.04 hours/night with SR versus AS in linear models adjusted for baseline outcome values. With SR versus AS, fasting insulin and homeostasis model assessment of insulin resistance (HOMA-IR) values were increased; the effects on HOMA-IR were more pronounced in postmenopausal women. The effects of SR on glucose metabolism were not mediated by changes in adiposity; when changes in adiposity were included as a covariate, the results were not altered in the full sample.

"Clinicians should educate patients on the crucial role of sleep for health and discuss strategies to increase sleep duration, which may protect against IR and the development of type 2 diabetes, and promote healthy life span in women," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2023-11-18 06:49

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords