Smoking + RA With Obstructive Pattern Shows Less Spirometry Decline
Medically reviewed by Drugs.com.
By Lori Solomon HealthDay Reporter
TUESDAY, June 25, 2024 -- Patients who have smoked with rheumatoid arthritis (RA) and an obstructive pattern may be a unique phenotype, according to a study published online June 17 in RMD Open.
Keigo Hayashi, M.P.H., from Brigham and Women's Hospital in Boston, and colleagues compared longitudinal changes in spirometric measures over five to seven years between 233 patients with RA and 37,735 non-RA comparators.
The researchers found that among never-smoking participants without an obstructive pattern, RA was significantly associated with more decline in annual changes in the percent-predicted forced expiratory volume in one second (FEV1 percent; β =−0.49). In ever smokers with ≥10 pack-years, those with RA exhibited significantly less FEV1 percent decline than non-RA comparators (β = 0.50). A more pronounced difference was seen among those with an obstructive pattern at baseline (β = 1.12). Similar results were seen for FEV1/ forced vital capacity (FVC) decline. There was no difference in the annual FVC percent change in RA versus non-RA.
"Further studies are required to explore the mechanisms and potential reversibility of systemic inflammation, autoimmunity and the impact of RA treatments on pulmonary function," the authors write.
Several authors disclosed ties to the pharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
Source: HealthDay
Posted : 2024-06-26 01:15
Read more
- Fatigue With Rheumatoid Arthritis Tied to Disease Activity, Education Level
- 'Dual Mutant' Seasonal Flu Virus Could Make Some Treatments Ineffective
- COVID-19 Vaccination Not Tied to Adverse Pregnancy Outcomes
- Bariatric Surgery Tied to Lower Risk of MACE, Death in Obesity, Sleep Apnea
- Abeona Therapeutics Provides Regulatory Update on Pz-cel
- ADA: Tirzepatide Reduces Apnea-Hypopnea Index in Moderate-to-Severe OSA
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- penginapan di alahan panjang
- nutrition faktory
- doksisiklin
- waist adalah
- kolonoskopi adalah
- obat glimepiride
- antiemetik adalah
- efek samping metformin
- sudut 45 derajat
- plasebo adalah
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions
- qulipta side effects anxiety
- repotrectinib side effects
- ibrance para que sirve
- foods to avoid while taking enbrel
- 反応 速度 鍛える
- baby shampoo eczema
- cdk inhibitor breast cancer
- xulane package insert
- loryna side effects
- keytruda pi
- estarylla vs sprintec
- pros and cons of junel birth control
- tissue plasminogen activator
- jolessa
- ワセリン ベビー パウダー
- tintes para piel morena
- parp 阻害 薬
- デスモイド
- erau ernie
- vasoplex side effects
- rutina de hombros
- merk pre workout
- 湾曲ペニス
- best work out shoes
- ウィニペグ大学
- transparent labs creatine hmb
- nutrition faktory
- メトホルミン 効果発現
- お 風呂 おもちゃ 赤ちゃん
- メトホルミン 副作用