Testosterone Use Not Tied to Gynecological Cancers in Transmasculine Individuals
By Lori Solomon HealthDay Reporter
FRIDAY, May 16, 2025 -- Short-term testosterone use among transmasculine and gender diverse (TMGD) individuals is not associated with an increased risk for gynecological cancers, according to a study published online May 12 in eClinicalMedicine.
Asra Vestering, M.D., from the Amsterdam University Medical Center, and colleagues evaluated the incidence of gynecological (pre-)malignancies among 1,955 TMGD individuals using testosterone treatment between Feb. 17, 1972, and Dec. 3, 2018.
The researchers found a median duration of testosterone usage of 1.7 years before hysterectomy and oophorectomy (median age, 24 years) and 3.1 years before vaginal and/or vulvar surgery or biopsy (median age, 29 years). No gynecological malignancies were seen, while expected incidence was ≤0.26 for all cancer types. Across samples, one ovarian borderline tumor, one case of simple endometrial hyperplasia, and one case of vulvar intraepithelial neoplasia (VIN) III were detected. The age-adjusted standardized incidence ratio for >VIN2 was 0.23.
"We found no increased risk of these cancers compared to women from the general population. None of these cancers were diagnosed in the entire participant group," Vestering said in a press release. "This is valuable information for both health care providers and transmasculine and gender-diverse people who are considering starting hormone therapy."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
Source: HealthDay
Posted : 2025-05-17 06:00
Read more

- FDA Grants Accelerated Approval to Avmapki Fakzynja Co-Pack (avutometinib capsules/defactinib tablets) for KRAS-Mutated Recurrent Low-Grade Serous Ovarian Cancer
- Climate Change Could Be Fueling Female Cancer Deaths
- Eating Healthier Can Protect Aging Brain
- Researchers Say Dance and Lullabies Are Learned, Not Hardwired
- Proinflammatory Foods Tied to Higher Risk of Death in Colon Cancer Patients
- Childhood Cancer Survivors Have Increased Risk for CKD, Hypertension
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Popular Keywords
- metformin obat apa
- alahan panjang
- glimepiride obat apa
- takikardia adalah
- erau ernie
- pradiabetes
- besar88
- atrofi adalah
- kutu anjing
- trakeostomi
- mayzent pi
- enbrel auto injector not working
- enbrel interactions
- lenvima life expectancy
- leqvio pi
- what is lenvima
- lenvima pi
- empagliflozin-linagliptin
- encourage foundation for enbrel
- qulipta drug interactions