Too Little or Too Much Sleep Ages Every Organ in Your Body

Medically reviewed by Carmen Pope, Senior Medical Editor, B. Pharm. Last updated on May 14, 2026.

via HealthDay

THURSDAY, May 14, 2026 — Your sleep habits may be affecting more than just your energy level. A new study says they could also impact how quickly every organ in your body ages.

Researchers analyzed data from nearly a half-million people in the United Kingdom to examine how sleep duration relates to aging across different organ systems.

Using advanced "biological aging clocks" powered by machine learning, the team measured aging in 17 systems, including the brain, heart, lungs, liver and immune system.

"In the liver, for example, we have an aging clock built with protein data, an aging clock of metabolic data, and an aging clock of imaging data," said lead author Junhao Wen, an assistant professor of radiology at Columbia University Vagelos College of Physicians and Surgeons in New York City. "This allows us to see whether sleep is distinctively associated with aging clocks derived from multiple omics and molecular layers."

The findings, published May 13 in the journal Nature, revealed a U-shaped pattern: People who slept fewer than 6 hours — or more than 8 hours — a night showed signs of faster biological aging throughout the body.

The healthiest aging patterns were seen in people who reported sleeping between 6.4 and 7.8 hours per night.

Short sleep was linked to a higher risk of many conditions, including depression, anxiety, obesity, type 2 diabetes, high blood pressure and heart disease.

Both short and long sleep were associated with lung conditions, including COPD and asthma, as well as digestive disorders such as gastritis and acid reflux.

The researchers said the findings highlight how deeply sleep is connected to overall body function — not just brain health.

Wen said that these findings support the idea that sleep plays an important role in maintaining organ health across the brain and body, including metabolic balance and a healthy immune system.

He added that future studies will explore whether improving sleep habits could help slow biological aging across different organs.

Sources

  • HealthDay TV, May 14, 2026
  • Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

    Source: HealthDay

    Read more

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords