Transvaginal Ultrasound Triage Strategy for Endometrial Cancer Not Reliable for Black Women at Risk

Follow Drugslib on

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

WEDNESDAY, July 10, 2024 -- For Black adults at risk for endometrial cancer (EC), a transvaginal ultrasonography triage strategy is not reliable, according to a study published online June 27 in JAMA Oncology.

Kemi M. Doll, M.D., from the University of Washington in Seattle, and colleagues examined false-negative probability using ultrasonography-measured endometrial thickness (ET) thresholds as triage for EC diagnosis among Black individuals who underwent hysterectomy in a retrospective diagnostic study of merged abstracted electronic health record data and secondary administrative data. The sample included 1,494 individuals with a uterus; 210 had EC.

The researchers found that the most common presenting diagnoses within 30 days of ultrasonography were fibroids, vaginal bleeding, and pelvic pain (78.1, 71.4, and 57.4 percent, respectively). There was an 11.4 percent probability that someone with EC would be classified as not having EC by applying the less than 5-mm ET threshold. At the 4-mm and 3-mm thresholds, the probability was 9.5 and 3.8 percent, respectively. At the 5-mm threshold, false-negative probability was similar among EC risk factor groups, including those with postmenopausal bleeding, body mass index >40, and age 50 years or older (12.4, 9.3, and 12.8 percent, respectively). Among those with fibroids on ultrasonography, the false-negative probability was similar (11.8 percent), while probability was higher with reported partial ET visibility and pelvic pain (26.1 and 14.5 percent, respectively).

"Among Black patients who underwent hysterectomy, a significant proportion of those with EC had ET below the range of diagnostic thresholds for detection," the authors write.

Several authors disclosed ties to the biopharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-07-11 01:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords