Ultrasonic Propulsion of Residual Kidney Stone Fragments Cuts Relapse

Follow Drugslib on

Medically reviewed by Carmen Pope, BPharm. Last updated on Oct 1, 2024.

By Elana Gotkine HealthDay Reporter

TUESDAY, Oct. 1, 2024 -- For patients with residual kidney stone fragments, the risk for relapse is lower with ultrasonic propulsion-facilitated clearance of fragments, and adverse events are mild, according to a study published online Aug. 14 in The Journal of Urology.

Matthew D. Sorensen, M.D., from the University of Washington School of Medicine in Seattle, and colleagues conducted a multicenter, prospective, randomized controlled trial involving adults with residual kidney stone fragments designed to examine whether ultrasonic propulsion to facilitate kidney stone fragment clearance reduces relapse. The primary outcome was relapse by five years or study end.

Participants were followed for a median of 3.0 years. The researchers found that the 40 patients in the treatment group had significantly longer time to relapse than the 42 in the control group. The restricted mean time to relapse was 52 percent longer in the treatment versus control group (1,530 ± 92 versus 1,009 ± 118 days), and the risk for relapse was lower, with eight versus 21 patients, respectively, experiencing relapse (hazard ratio, 0.30). Overall, 63 and 5 percent of patients in the treatment and control groups, respectively, passed fragments within three weeks of treatment. Adverse events were mild, transient, and self-resolving and occurred in 63 percent of patients in the treatment group and 40 percent of patients in the control group.

"Our study showed that removing residual fragments by ultrasonic propulsion reduced relapse as measured by future stone growth or stone-related urgent medical visit or surgery," the authors write.

Several authors disclosed ties to SonoMotion, and one author disclosed ties to Philips Healthcare.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-10-02 06:00

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords