Varenicline, Nicotine-Containing E-Cigarettes Help in Quitting Smoking

Follow Drugslib on

Medically reviewed by Carmen Pope, BPharm. Last updated on June 19, 2024.

By Lori Solomon HealthDay Reporter

WEDNESDAY, June 19, 2024 -- Varenicline and nicotine-containing electronic cigarettes (ECs) are both effective in helping individuals in quitting smoking conventional cigarettes, according to a study published online June 17 in JAMA Internal Medicine.

Anna Tuisku, Ph.D., from Lapland Central Hospital in Finland, and colleagues randomly assigned 458 participants (aged 25 to 75) who smoked daily and had volunteered to quit smoking to either 18 mg/mL of nicotine-containing ECs together with placebo tablets, varenicline with standard dosing together with nicotine-free ECs, or placebo tablets together with nicotine-free ECs.

The researchers found that self-reported seven-day conventional cigarette smoking abstinence as confirmed by the exhaled carbon monoxide level on week 26 occurred in 40.4 percent in the EC group, 43.8 percent in the varenicline group, and 19.7 percent in the placebo group. There were significant differences between placebo and ECs (risk difference [RD], 20.7 percent) and varenicline (RD, 24.1 percent). The difference was not significant between ECs and varenicline (RD, 3.4 percent).

"When balancing the benefits of nicotine-containing ECs in smoking cessation with the known harms as well as the uncertainty surrounding their long-term harm consumption, it seems that they may have a role in reducing tobacco-related damage to health in adults who substantially depend on nicotine and have been smoking for many years and, despite several attempts, have been unable to quit smoking conventional cigarettes," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

Source: HealthDay

Posted : 2024-06-20 03:15

Read more

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords