What Are the Chances of Contracting HIV After One Exposure?

It’s possible to contract HIV after one brief exposure, but it’s statistically unlikely except in cases of blood transfusion. If concerned about potential exposure to HIV, ask a healthcare professional about the medication PEP.

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HIV is a virus that weakens your immune system by killing CD4 cells, which are a type of immune cell. People living with untreated HIV are more vulnerable to disease.

HIV can progress into AIDS if left untreated. The World Health Organization estimated at the end of 2020 that about 37.7 million people are living with HIV worldwide.

HIV is transmitted between people through bodily fluids. Unprotected anal or vaginal sex and sharing needles are common ways people contract HIV. People can also transmit HIV to their babies during pregnancy or while breastfeeding.

HIV can be transmitted even with a single, brief exposure. The authors of a 2014 review of studies estimated chances of infection for various types of exposures. Based on their data, the table below shows the estimated risk of contracting HIV for a single exposure event:

Exposure typeEstimated infections per 10,000 exposuresEstimated risk for a single exposure
Blood transfusion9,25092.5%
Needle-sharing630.6%
Receiving anal sex1381.4%
Insertive anal sex110.1%
Receiving penile-vaginal sex80.1%
Insertive penile-vaginal sex4

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