Platelet aggregation inhibitors

What are Platelet aggregation inhibitors?

Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation.

Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation). It irreversibly inhibits the enzyme cyclo-oxygenase, which leads to reduction in thromboxane synthesis in platelets and prostacyclin in vascular endothelial cells. The vascular endothelium recovers and can synthesize more prostacyclin but thromboxane synthesis only recovers after new platelets are formed.

Platelet aggregation inhibitors are used acutely in myocardial infarction, atrial fibrillation, following coronary bypass, angioplasty and stenting. It is also used as prophylaxis to prevent myocardial infarction and stroke.

List drug with Platelet aggregation inhibitors

Drug Name
Aggrenox
Generic name: Aspirin And Dipyridamole
Aspirin and dipyridamole
Generic name: Aspirin And Dipyridamole
Aspirin and omeprazole
Generic name: Aspirin And Omeprazole
Clopidogrel
Generic name: Clopidogrel
Brilinta
Generic name: Ticagrelor
Cablivi
Generic name: Caplacizumab
Cangrelor
Generic name: Cangrelor
Caplacizumab
Generic name: Caplacizumab
Caplacizumab-yhdp
Generic name: Caplacizumab-yhdp
Effient
Generic name: Prasugrel
Kengreal
Generic name: Cangrelor
Plavix
Generic name: Clopidogrel
Prasugrel
Generic name: Prasugrel
Ticagrelor
Generic name: Ticagrelor
Ticlid
Generic name: Ticlopidine
Yosprala
Generic name: Aspirin And Omeprazole

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