Yosprala
Generic name: Aspirin And Omeprazole
Drug class:
Platelet aggregation inhibitors
Usage of Yosprala
Yosprala contains a combination of aspirin and Omeprazole. Aspirin is as platelet aggregation inhibitor. It also reduces substances in the body that cause pain, fever, and inflammation. Omeprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
Yosprala is used to help lower the risk of heart problems, strokes, or death in people who have HAD certain conditions related to blood clots, including angina (chest pain), a past heart attack, or a stroke or a "mini stroke."
Yosprala is also used in people who have had surgery to improve blood flow to the heart and also have another condition that is already being treated with aspirin.
Omeprazole helps reduce the risk of stomach ulcers that may be caused by aspirin, especially in people who are 55 or older, or those who have had stomach ulcers in the past.
Yosprala side effects
Get emergency medical help if you have signs of an allergic Reaction to Yosprala: sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Taking Yosprala long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.
If you use this medicine for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
Common Yosprala side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Yosprala
You should not use Yosprala if you are allergic to aspirin or omeprazole, or if:
Yosprala should not be used to treat a sudden onset of heart attack or stroke symptoms (chest pain, sudden numbness or weakness, slurred speech).
Yosprala is not approved for use by anyone younger than 18 years old. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.
Tell your doctor if you have ever had:
You may be more likely to have a broken bone in your hip, wrist, or spine while taking Yosprala long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.
Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.
Yosprala may temporarily affect your ability to get pregnant. Talk with your doctor if this concerns you.
You should not breastfeed while using Yosprala.
Relate drugs
- Aggrenox
- Aspirin and dipyridamole
- Aspirin and omeprazole
- Clopidogrel
- Brilinta
- Cablivi
- Cangrelor
- Caplacizumab
- Caplacizumab-yhdp
- Effient
- Kengreal
- Plavix
- Prasugrel
- Ticagrelor
- Ticlid
- Yosprala
How to use Yosprala
Usual Adult Dose of Yosprala for Thromboembolic Stroke Prophylaxis:
One tablet (aspirin 81 mg-omeprazole 40 mg or aspirin 325 mg-omeprazole 40 mg) orally once a day at least 60 minutes before a meal Comments: -Generally, 81 mg of aspirin has been accepted as an effective dose for secondary cardiovascular prevention; the current clinical practice guidelines should be referenced when considering the need for 325 mg of aspirin. Use: For patients requiring secondary prevention of cardiovascular and cerebrovascular events who are at risk of developing aspirin associated gastric ulcers.
Usual Adult Dose of Yosprala for Ischemic Stroke -- Prophylaxis:
One tablet (aspirin 81 mg-omeprazole 40 mg or aspirin 325 mg-omeprazole 40 mg) orally once a day at least 60 minutes before a meal Comments: -Generally, 81 mg of aspirin has been accepted as an effective dose for secondary cardiovascular prevention; the current clinical practice guidelines should be referenced when considering the need for 325 mg of aspirin. Use: For patients requiring secondary prevention of cardiovascular and cerebrovascular events who are at risk of developing aspirin associated gastric ulcers.
Usual Adult Dose of Yosprala for Cardiovascular Risk Reduction:
One tablet (aspirin 81 mg-omeprazole 40 mg or aspirin 325 mg-omeprazole 40 mg) orally once a day at least 60 minutes before a meal Comments: -Generally, 81 mg of aspirin has been accepted as an effective dose for secondary cardiovascular prevention; the current clinical practice guidelines should be referenced when considering the need for 325 mg of aspirin. Use: For patients requiring secondary prevention of cardiovascular and cerebrovascular events who are at risk of developing aspirin associated gastric ulcers.
Usual Adult Dose of Yosprala for Gastric Ulcer Prophylaxis:
One tablet (aspirin 81 mg-omeprazole 40 mg or aspirin 325 mg-omeprazole 40 mg) orally once a day at least 60 minutes before a meal Comments: -Generally, 81 mg of aspirin has been accepted as an effective dose for secondary cardiovascular prevention; the current clinical practice guidelines should be referenced when considering the need for 325 mg of aspirin. Use: For patients requiring secondary prevention of cardiovascular and cerebrovascular events who are at risk of developing aspirin associated gastric ulcers.
Warnings
You should not use Yosprala if you take medicine that contains rilpivirine, or if you've ever had an asthma attack or severe allergic reaction after taking aspirin or another NSAID (nonsteroidal anti-inflammatory drug).
Aspirin can make you bleed more easily. Call your doctor if you have any unusual bleeding or bruising, or if you cough up blood or have bloody or tarry stools.
Omeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.
Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.
Omeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
You may be more likely to have a broken bone while taking Yosprala long term or more than once per day.
Do not stop using Yosprala suddenly, even if you feel fine.
What other drugs will affect Yosprala
Sometimes it is not safe to use certain medications at the SAMe time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Tell your doctor about all your current medicines. Many drugs can interact with aspirin and omeprazole, especially:
This list is not complete and many other drugs may interact with aspirin and omeprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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