Aspirin and dipyridamole

Generic name: Aspirin And Dipyridamole
Brand names: Aggrenox
Dosage form: oral capsule, extended release (25 mg-200 mg)
Drug class: Platelet aggregation inhibitors

Usage of Aspirin and dipyridamole

Aspirin and dipyridamole is a combination medicine used to reduce the risk of stroke in people who have had blood clots or a "mini-stroke" (also called a transient ischemic attack or TIA).

Aspirin and dipyridamole may also be used for purposes not listed in this medication guide.

Aspirin and dipyridamole side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Aspirin and dipyridamole may cause serious side effects. Call your doctor at once if you have:

new or worsening chest pain;

a light-headed feeling, like you might pass out;

hearing problems, ringing in your ears;

liver problems--upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

signs of stomach bleeding--stomach pain, severe heartburn, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or

signs of bleeding in the brain--confusion, memory problems, severe headache, fainting.

Common side effects of aspirin and dipyridamole may include:

headache;

heartburn, upset stomach;

nausea, stomach pain; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Aspirin and dipyridamole

You should not use this medicine if you are allergic to aspirin or dipyridamole, or if you have:

asthma in combination with polyps in your nose; or

if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID (non-steroidal anti-inflammatory drug).

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children.

Tell your doctor if you have ever had:

a stomach ulcer or bleeding;

bleeding problems;

heart problems;

low blood pressure; or

myasthenia gravis.

Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Relate drugs

How to use Aspirin and dipyridamole

Usual Adult Dose for Ischemic Stroke -- Prophylaxis:

Aspirin 25 mg-Dipyridamole 200 mg orally twice a dayComments: If intolerable headaches occur during initial treatment, switch to aspirin 25 mg-dipyridamole 200 mg orally at bedtime and low-dose aspirin in the morning; return to usual regimen as soon as possible, usually within 1 week.Use: To reduce the risk of stroke in patients who have had transient ischemia of the brain or complete ischemic stroke due to thrombosis.

Warnings

You should not use aspirin and dipyridamole if you have asthma and also have polyps in your nose, or if you are allergic to aspirin or an NSAID (nonsteroidal anti-inflammatory drug).

Aspirin and dipyridamole can increase your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.

What other drugs will affect Aspirin and dipyridamole

Tell your doctor about all your other medicines, especially:

acetazolamide;

methotrexate;

probenecid;

heart or blood pressure medication, including a diuretic or "water pill";

medicine to treat Alzheimer's disease;

medicines used to treat or prevent blood clots, such as anagrelide, heparin, or warfarin (Coumadin, Jantoven);

oral diabetes medicine;

seizure medication; or

an NSAID--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect aspirin and dipyridamole, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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