Iloperidone

Generic name: Iloperidone
Brand names: Fanapt
Dosage form: oral tablet (1 mg; 1 mg-2 mg-4 mg-6 mg; 10 mg; 12 mg; 2 mg; 4 mg; 6 mg; 8 mg)
Drug class: Atypical antipsychotics

Usage of Iloperidone

Iloperidone is an antipsychotic medication that is used to treat schizophrenia in adults.

Iloperidone may also be used for purposes not listed in this medication guide.

Iloperidone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

High doses or long-term use of iloperidone can cause a serious movement disorder that may not be reversible. The longer you use iloperidone, the more likely you are to develop this disorder, especially if you are an older adult.

Iloperidone may cause serious side effects. Call your doctor at once if you have:

fast or pounding heartbeats, fluttering in your chest;

a light-headed feeling, like you might pass out;

uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);

tremors, slow muscle movement, muscles pain or stiffness;

confusion, agitation, thoughts of hurting yourself;

loss of bladder control;

penis erection that is painful or lasts 4 hours or longer;

high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor;

low white blood cell counts--fever, chills, sore throat, mouth sores, skin sores, cough, trouble breathing; or

severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;

Older adults may be more likely to have side effects from iloperidone.

Common side effects of iloperidone may include:

weight gain;

dizziness, drowsiness, tired feeling;

dry mouth, stuffy nose; or

fast heart rate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Iloperidone

You should not use iloperidone if you are allergic to it.

Iloperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

Tell your doctor if you have ever had:

trouble swallowing;

long QT syndrome (in you or a family member);

a seizure;

diabetes, or risk factors such as being overweight or having a family history of diabetes;

breast cancer;

high cholesterol or triglycerides;

an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

low bone mineral density; or

liver disease.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of iloperidone on the baby.

Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking iloperidone without your doctor's advice.

You should not breastfeed while you are taking iloperidone.

Iloperidone is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use Iloperidone

Usual Adult Dose for Schizophrenia:

Initial dose: 1 mg orally twice a dayMaintenance dose: 6 to 12 mg twice a dayMaximum dose: 24 mg/dayComments:-This drug must be titrated slowly to avoid orthostatic hypotension.-Control of symptoms may be delayed during the first 1 to 2 weeks of treatment because of the need to titrate slowly.-Treatment should be increased in increments of not more than 2 mg twice daily as tolerated.-Healthcare providers should periodically re-evaluate the long-term risks and benefits of the drug for the individual patient.Use: Treatment of schizophrenia

Warnings

Iloperidone is not approved for use in older adults with dementia-related psychosis.

What other drugs will affect Iloperidone

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Iloperidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Using iloperidone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Many drugs can affect iloperidone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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