Mesna oral/injection
Generic name: Mesna (oral/injection)
Brand names: Mesnex
Drug class:
Antineoplastic detoxifying agents
Usage of Mesna oral/injection
Mesna is used to prevent bleeding in the bladder (hemorrhagic cystitis) during chemotherapy with ifosfamide (Ifex).
Mesna will not prevent other side effects caused by ifosfamide.
Mesna may also be used for purposes not listed in this medication guide.
Mesna oral/injection side effects
Get emergency medical help if you have signs of an allergic reaction or severe skin reaction:
Mesna may cause serious side effects. Call your doctor at once if you have:
Common side effects of mesna may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Mesna oral/injection
You should not use mesna if you are allergic to mesna, edetate sodium, sodium hydroxide, or Benzyl Alcohol.
Tell your doctor if you are allergic to any medicine.
Although mesna is not expected to harm an unborn baby, ifosfamide can harm an unborn baby if the mother or the father is using this medicine.
Do not breast-feed while using mesna or ifosfamide, and for at least 1 week after your last dose.
Mesna injection contains an ingredient that can cause serious side effects or death in premature or low-birthweight babies. Mesna tablets do not contain this ingredient. Mesna injection should not be given to a premature or low birth weight infant.
Relate drugs
- Amifostine
- Ethyol
- Mesna (Intravenous)
- Mesna (Oral)
- Mesna oral/injection
- Mesnex (Mesna Intravenous)
- Mesnex (Mesna Oral)
- Mesnex oral/injection
- Pedmark
How to use Mesna oral/injection
Before and during treatment with mesna, you may need frequent urine tests.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Mesna injection is given as an infusion into a vein. A healthcare provider will give you this injection at the same time you receive ifosfamide.
Oral mesna is taken by mouth, usually 2 and 6 hours after you receive ifosfamide.
Mesna is given either in a series of 3 injections spaced 4 hours apart, or as a single injection followed by 2 oral doses spaced 2 and 6 hours later.
Follow your doctor's dosing instructions very carefully.
Call your doctor if you vomit within 2 hours after taking oral mesna. You may need to take another oral dose or receive a mesna injection.
Tell your doctor if you have red or pink colored urine. This may be a sign that your ifosfamide dose needs to be changed.
Drink at least 1 to 2 liters (32 to 64 ounces) of liquid each day while you are using mesna.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using mesna.
Store mesna tablets at room temperature away from moisture and heat.
Warnings
Get emergency medical help if you have signs of a serious reaction: fever, nausea, vomiting, racing heartbeats, hives, rash or redness, skin pain or swelling, blisters or peeling, joint or muscle pain, feeling light-headed, trouble breathing, mouth sores, or swelling in your face or throat.
What other drugs will affect Mesna oral/injection
Other drugs may affect mesna, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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