Metoprolol

Generic name: Metoprolol
Drug class: Cardioselective beta blockers

Usage of Metoprolol

Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).

Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure).

Metoprolol is also used to lower your risk of death or needing to be hospitalized for heart failure.

Metoprolol injection is used during the early phase of a heart attack to lower the risk of death.

Metoprolol side effects

Get emergency medical help if you have signs of an allergic reaction to metoprolol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Metoprolol may cause serious side effects. Call your doctor at once if you have:

very slow heartbeats;

a light-headed feeling, like you might pass out;

shortness of breath (even with mild exertion), swelling, rapid weight gain; or

cold feeling in your hands and feet.

Common side effects of metoprolol may include:

dizziness;

tired feeling;

depression;

confusion;

memory problems;

nightmares;

trouble sleeping;

diarrhea;

mild itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Metoprolol

You should not use this medicine if you are allergic to metoprolol, or other beta-blockers (atenolol, carvedilol, labetalol, nadolol, nebivolol, propranolol, sotalol, and others), or if you have:

a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate;

severe circulation problems;

severe heart failure (that required you to be in the hospital); or

a history of slow heart beats that have caused you to faint.

To make sure this medicine is safe for you, tell your doctor if you have:

asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;

diabetes (taking metoprolol may make it harder for you to tell when you have low blood sugar);

liver disease;

congestive heart failure;

problems with circulation (such as Raynaud's syndrome);

a thyroid disorder; or

pheochromocytoma (tumor of the adrenal gland).

Do not give this medicine to a child without medical advice.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether metoprolol will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Ask a doctor before using this medicine if you are breast-feeding. Metoprolol can pass into breast milk and may cause dry skin, dry mouth, diarrhea, constipation, or slow heartbeats in your baby.

Relate drugs

How to use Metoprolol

Usual Adult Dose for Hypertension:

Metoprolol Tartrate Immediate Release Tablets: Initial dose: 100 mg orally per day in single or divided doses Maintenance dose: 100 to 450 mg orally per day. Metoprolol Succinate Extended Release Tablets: Initial dose: 25 to 100 mg orally once a day Maintenance dose: 100 to 400 mg orally once a day.

Usual Adult Dose for Angina Pectoris:

Initial dose: -Metoprolol tartrate immediate release tablets: 50 mg orally twice a day -Metoprolol succinate extended release tablets: 100 mg orally once a day Maintenance dose: 100 to 400 mg per day.

Usual Adult Dose for Myocardial Infarction:

Metoprolol Tartrate : Early Treatment: Initial dose: 5 mg IV every 2 minutes as tolerated for 3 doses -Patients tolerant of full IV dose (15 mg): 50 mg orally every 6 hours starting 15 minutes after the last IV dose and continued for 48 hours -Patients intolerant of full IV dose (15 mg): 25 or 50 mg orally every 6 hours depending on the degree of intolerance starting 15 minutes after the last IV dose or as soon as their clinical condition allows Late Treatment: Maintenance dose: 100 mg orally twice a day.

Usual Adult Dose for Congestive Heart Failure:

Metoprolol Succinate Extended Release Tablets: 25 mg orally once a day (12.5 mg orally once a day in patients with more severe heart failure); double dose every 2 weeks to highest tolerated dose or up to 200 mg orally once a day.

Usual Pediatric Dose for Hypertension:

Metoprolol Succinate Extended Release Tablets: 6 Years or Older: Initial dose: 1 mg/kg orally once a day (not to exceed 50 mg orally once a day) Maximum dose: 2 mg/kg (or 200 mg) orally once a day.

Warnings

You should not use metoprolol if you have a serious heart problem (heart block, sick sinus syndrome, slow heart rate), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting.

What other drugs will affect Metoprolol

Tell your doctor about all your current medicines. Many drugs can interact with metoprolol, especially:

any other heart or blood pressure medications;

epinephrine (Epi-Pen);

an antidepressant;

an ergot medicine--dihydroergotamine, ergonovine, ergotamine, methylergonovine; or

an MAO inhibitor--isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine.

This list is not complete and many other drugs may interact with metoprolol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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