Nuplazid

Generic name: Pimavanserin
Drug class: Atypical antipsychotics

Usage of Nuplazid

Nuplazid is an antipsychotic medicine that works by changing the actions of chemicals in the brain.

Nuplazid is used to treat hallucinations and delusions caused by psychosis that is related to Parkinson's disease.

Nuplazid side effects

Get emergency medical help if you have signs of an allergic reaction to Nuplazid: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

fast or pounding heartbeats, fluttering in your chest;

shortness of breath; or

sudden dizziness (like you might pass out).

Common Nuplazid side effects may include:

confusion; or

swelling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Nuplazid

Nuplazid may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

You should not use Nuplazid if you are allergic to pimavanserin.

Tell your doctor if you have ever had:

a heart rhythm disorder;

long QT syndrome (in you or a family member);

kidney disease; or

an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Relate drugs

How to use Nuplazid

Usual Adult Dose for Psychosis:

34 mg (as two 17 mg tablets) orally once a day Comment: This drug does not require titration. Use: Treatment of hallucinations and delusions associated with Parkinson's disease psychosis

Warnings

Nuplazid is not approved for use in older adults with dementia-related psychosis.

What other drugs will affect Nuplazid

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Your pimavanserin dose may need to be adjusted if you use certain other medications. It is very important to tell your doctor if you start or stop using any other medications.

Nuplazid can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Many drugs can interact with pimavanserin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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