Olanzapine
Generic name: Olanzapine (oral)
Drug class:
Atypical antipsychotics
Usage of Olanzapine
Olanzapine is an antipsychotic medication that is used to treat psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children at least 13 years old.
Olanzapine is also used together with fluoxetine (Prozac) to treat episodes of depression in adults and children at least 10 years old who have bipolar I disorder.
Olanzapine may also be used for purposes not listed in this medication guide.
Olanzapine side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
High doses or long-term use of olanzapine can cause a serious movement disorder that may not be reversible. The longer you use olanzapine, the more likely you are to develop this disorder, especially if you are a woman or an older adult.
Olanzapine may cause serious side effects. Call your doctor at once if you have:
Common side effects of olanzapine may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Olanzapine
You should not take olanzapine if you are allergic to it.
Olanzapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.
Tell your doctor if you have ever had:
Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking olanzapine without your doctor's advice.
Olanzapine can pass into breast milk. If you are breastfeeding, tell your doctor if you notice severe drowsiness, irritability, feeding problems, tremors, or unusual muscle movements in the nursing baby.
The olanzapine orally disintegrating tablet (Zyprexa Zydis) may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
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How to use Olanzapine
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Olanzapine can be taken with or without food.
Remove an orally disintegrating tablet (Zyprexa Zydis) from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves.
Olanzapine can cause high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis.
You may gain weight or have high cholesterol and triglycerides (types of fat) while taking olanzapine, especially if you are a teenager. You may need frequent blood tests.
Call your doctor if your symptoms do not improve, or if they get worse while using olanzapine.
Do not stop using olanzapine suddenly, even if you feel fine. Stopping suddenly may cause serious side effects.
Olanzapine is sometimes used together with other antipsychotic medications or antidepressants. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice.
Medication may be only part of a complete program of treatment that also includes counseling and other psychological support programs. Follow your doctor's instructions.
Store at room temperature away from moisture, heat, and light.
Warnings
Olanzapine is not approved for use in older adults with dementia-related psychosis.
What other drugs will affect Olanzapine
Taking olanzapine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Other drugs may affect olanzapine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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