Generic name: Peramivir
Brand names: Rapivab
Dosage form: intravenous solution (10 mg/mL)
Drug class: Neuraminidase inhibitors

Usage of Peramivir

Peramivir works by preventing an enzyme in the body from releasing virus from infected cells.

Peramivir is used to treat influenza in adults and children who are at least 2 years old, who have had flu symptoms for up to 2 days.

Peramivir may also be used for purposes not listed in this medication guide.

Peramivir side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Peramivir may cause serious side effects. Call your doctor at once if you have:

  • new or worsening flu symptoms; or
  • confusion, hallucinations, unusual thoughts or behavior.
  • Common side effects of peramivir may include:

  • diarrhea;
  • constipation; or
  • sleep problems (insomnia).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Peramivir

    Tell your doctor if you have ever had:

  • kidney disease (or if you are on dialysis); or
  • if you have received a nasal flu vaccine (FluMist) within the past 2 weeks.
  • It is not known whether peramivir will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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    How to use Peramivir

    Usual Adult Dose for Influenza:

    600 mg IV once as a single doseUse: For the treatment of acute uncomplicated influenza in patients symptomatic no more than 2 days

    Usual Pediatric Dose for Influenza:

    6 months to 12 years: 12 mg/kg IV once as a single dose-Maximum dose: 600 mg/dose13 years or older: 600 mg IV once as a single doseUse: For the treatment of acute uncomplicated influenza in patients symptomatic no more than 2 days


    Before you receive peramivir, tell your doctor about all your medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding.

    What other drugs will affect Peramivir

    Other drugs may affect peramivir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.


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