Pimavanserin

Generic name: Pimavanserin
Brand names: Nuplazid
Drug class: Atypical antipsychotics

Usage of Pimavanserin

Pimavanserin is an antipsychotic medicine that works by changing the actions of chemicals in the brain.

Pimavanserin is used to treat hallucinations and delusions caused by psychosis that is related to Parkinson's disease.

Pimavanserin may also be used for purposes not listed in this medication guide.

Pimavanserin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Pimavanserin may cause serious side effects. Call your doctor at once if you have:

fast or pounding heartbeats, fluttering in your chest;

shortness of breath; or

sudden dizziness (like you might pass out).

Common side effects of pimavanserin may include:

confusion; or

swelling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Pimavanserin

Pimavanserin may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

You should not use pimavanserin if you are allergic to it.

Tell your doctor if you have ever had:

a heart rhythm disorder;

long QT syndrome (in you or a family member);

kidney disease; or

an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

Tell your doctor if you are pregnant or breastfeeding.

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How to use Pimavanserin

Usual Adult Dose for Psychosis:

34 mg (as two 17 mg tablets) orally once a dayComment: This drug does not require titration.Use: Treatment of hallucinations and delusions associated with Parkinson's disease psychosis

Warnings

Pimavanserin is not approved for use in older adults with dementia-related psychosis.

What other drugs will affect Pimavanserin

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Your pimavanserin dose may need to be adjusted if you use certain other medications. It is very important to tell your doctor if you start or stop using any other medications.

Pimavanserin can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Many drugs can affect pimavanserin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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