Prasugrel
Generic name: Prasugrel
Brand names: Effient
Dosage form: oral tablet (10 mg; 5 mg)
Drug class:
Platelet aggregation inhibitors
Usage of Prasugrel
Prasugrel is used in people who've had a balloon angioplasty to open blocked arteries after having a heart attack or severe chest pain. Prasugrel may help lower your risk of having another heart attack or stroke.
Prasugrel may also be used for other purposes not listed in this medication guide.
Prasugrel side effects
Get emergency medical help if you have signs of an allergic reaction: hives; dizziness, chest pain, difficulty breathing; swelling of your face, lips, tongue, or throat.
Prasugrel increases your risk of bleeding, which can be severe or life-threatening.
Prasugrel may cause serious side effects. Call your doctor at once if you have:
The risk of bleeding is higher in older adults.
Common side effects of prasugrel may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Prasugrel
You should not use prasugrel if you are allergic to it, or if you have:
Tell your doctor if you have ever had:
Tell your doctor if you are pregnant or breastfeeding.
Relate drugs
- Aggrenox
- Aspirin and dipyridamole
- Aspirin and omeprazole
- Clopidogrel
- Brilinta
- Cablivi
- Cangrelor
- Caplacizumab
- Caplacizumab-yhdp
- Effient
- Kengreal
- Plavix
- Prasugrel
- Ticagrelor
- Ticlid
- Yosprala
How to use Prasugrel
Usual Adult Dose for Acute Coronary Syndrome:
Initial dose: 60 mg orally onceMaintenance dose: 10 mg orally once a dayComments:-No clear benefit was observed when the loading dose of this drug was administered prior to diagnostic coronary angiography compared to at the time of percutaneous coronary intervention (PCI); however, risk of bleeding was increased with early administration in patients undergoing PCI or early coronary artery bypass graft surgery (CABG).-Aspirin 75 to 325 mg daily should be taken with this drug.Use: To reduce the rate of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be managed with PCI for unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), or ST segment elevation myocardial infarction (STEMI).
Usual Geriatric Dose for Acute Coronary Syndrome:
65 to less than 75 years:-Initial dose: 60 mg orally once-Maintenance dose: 10 mg orally once a day75 years or older: Use is generally not recommended in such patients, except in high-risk situations (e.g., diabetes or prior myocardial infarction) when benefit outweighs risk.Comments:-No clear benefit was observed when the loading dose of this drug was administered prior to diagnostic coronary angiography compared to at the time of percutaneous coronary intervention (PCI); however, risk of bleeding was increased with early administration in patients undergoing PCI or early coronary artery bypass graft surgery (CABG).-Aspirin 75 to 325 mg daily should be taken with this drug.Use: To reduce the rate of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be managed with PCI for unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), or ST segment elevation myocardial infarction (STEMI).
Warnings
Prasugrel increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.
You may need to stop using the medicine for a short time before any surgery or dental treatment. Do not stop taking prasugrel unless your doctor tells you to.
What other drugs will affect Prasugrel
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect prasugrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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