ZyPREXA injection

Generic name: Olanzapine (injection)
Drug class: Atypical antipsychotics

Usage of ZyPREXA injection

Olanzapine is an antipsychotic medication that is used to treat symptoms of schizophrenia in adults. Olanzapine injection is not for daily use to treat any psychotic condition.

Olanzapine injection is available only under a special program. You must be registered in the program and understand the risks and benefits of using this medication.

Olanzapine injection may also be used for purposes not listed in this medication guide.

ZyPREXA injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Olanzapine injection can cause serious symptoms if the medicine gets into your bloodstream too fast. During the first 3 hours after your injection you will be watched for the following signs:

severe dizziness, drowsiness, or weakness;

confusion, anxiety, feeling angry or hostile;

feeling nervous or shaky;

trouble walking or talking;

seizure (convulsions); or

a light-headed feeling, like you might pass out.

ZyPREXA may cause serious side effects. Call your doctor at once if you have:

twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;

trouble speaking or swallowing;

signs of dehydration--if you feel very thirsty or hot, are unable to urinate, and have heavy sweating or hot and dry skin;

high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor; or

severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors.

Common side effects of ZyPREXA may include:

headache, back pain;

weight gain (more likely in teenagers), increased appetite;

drowsiness;

dry mouth, nausea, vomiting, diarrhea;

sinus pain, runny or stuffy nose, cough; or

pain where the injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking ZyPREXA injection

You should not receive this medication if you are allergic to olanzapine.

Olanzapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.

If possible before you receive olanzapine injection, tell your doctor if you have ever had:

suicidal thoughts or actions;

liver disease;

heart disease, high or low blood pressure;

high cholesterol or triglycerides;

a stroke, including "mini-stroke";

breast cancer;

a seizure;

Alzheimer's disease;

diabetes or high blood sugar;

an enlarged prostate;

bowel problems; or

narrow-angle glaucoma.

Tell your doctor if you are pregnant. Using antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn.

Tell your doctor if you are breastfeeding. Olanzapine can pass into breast milk and may cause side effects in the nursing baby.

In an emergency, you may not be able to tell caregivers if you are pregnant or breastfeeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

Olanzapine injection is not approved for use by anyone younger than 18 years old.

Relate drugs

How to use ZyPREXA injection

Olanzapine is injected into a muscle. You will receive this injection in a clinic or hospital setting.

An olanzapine injection is usually given only once. If you still have symptoms after 2 hours, your caregivers may use a second or third dose.

Olanzapine injection can cause symptoms of delirium (sudden severe confusion, disorientation, agitation, problems with speech or walking), or drowsiness severe enough for you to lapse into a coma. You will be watched closely for at least 3 hours after your injection.

Warnings

Olanzapine injection is not approved for use in older adults with dementia-related psychosis.

What other drugs will affect ZyPREXA injection

Using olanzapine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect olanzapine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.