How long does it take for it to work?

Drugs.com

Official answer

by Drugs.com

Vumerity (diroximel fumarate) is a delayed-release capsule used to treat relapsing forms of the autoimmune disorder multiple sclerosis. It is thought to have an effect as early as 24 weeks after patients start taking it.

MS is a condition in which a person’s own immune system mistakenly attacks the central nervous system (CNS), causing inflammation and damage to myelin, which forms fatty sheaths around nerve cells to protect them. It is not yet known exactly how Vumerity works in the treatment of MS, but it has anti-inflammatory and anti-oxidative properties.

Vumerity contains diroximel fumarate. Diroximel fumarate is rapidly converted in the body to monomethyl fumarate (MMF), which is the same active metabolite Tecfidera (dimethyl fumarate) has.

The results of clinical studies investigating Tecfidera were used to gain FDA approval for Vumerity, given that they both have the same active metabolite, MMF.

In an analysis of data from the phase III DEFINE and CONFIRM studies, which looked at the effects of Tecfidera on health-related quality of life, the drug was found to start working as early as 24 weeks after it was started, although it can take up to 2 years to for its full effects to be seen.

Related medical questions

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Popular Keywords