Jynneos

Generic name: Smallpox And Monkeypox Vaccine
Drug class: Viral vaccines

Usage of Jynneos

Jynneos is used to help prevent smallpox and monkeypox diseases.

Like any vaccine, Jynneos may not provide protection from disease in every person.

Jynneos is for use in adults 18 years of age and older who are determined to be at high risk of contracting smallpox or monkeypox infection.

Jynneos is also authorized for emergency use to prevent monkeypox disease in people younger than 18 years of age who are determined to be at high risk of monkeypox infection.

Jynneos side effects

Get emergency medical help if you have signs of an allergic Reaction to Jynneos: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Jynneos side effects may include:

  • pain, redness, swelling, or itching where the vaccine was injected;
  • muscle pain;
  • headache;
  • tiredness;
  • nausea; or
  • chills.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1 800 822 7967.

    Before taking Jynneos

    You should not receive Jynneos if you have ever had a life-threatening allergic reaction to a smallpox or monkeypox vaccine.

    Tell your doctor if you have a weak immune system caused by receiving certain medicines such as steroids, chemotherapy or radiation.

    Tell your doctor if you are pregnant or breastfeeding.

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    How to use Jynneos

    Usual Adult Dose for Prevention of Smallpox and Monkeypox:

    Standard Regimen: Two suBCUTAneous doses of 0.5 mL each, 4 weeks apart.

    Use: Prevention of smallpox and monkeypox disease in adults 18 years or older at high risk of infection.

    Alternative Regimen (Emergency Use Authorization): Two intradermal doses of 0.1 mL each, 4 weeks apart (used to increase supply of vaccine doses during a public health emergency).

    Use: Prevention of monkeypox disease in adults 18 years or older at high risk of infection.

    Usual Pediatric/Adolescent Dose for Prevention of Monkeypox:

    Standard Regimen (Emergency Use Authorization): Two subcutaneous doses of 0.5 mL each, 4 weeks apart. 

    Use: Prevention of monkeypox disease in people younger than 18 years at high risk of infection.

    Warnings

    Use Jynneos only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

    Jynneos can cause a severe allergic reaction. Medical treatment must be available to treat any anaphylactic reactions following administration.

    Immunocompromised persons, including those receiving immunosuppressive therapy, may have a diminished immune response to this vaccine.

    Vaccination with Jynneos may not protect all patients.

    What other drugs will affect Jynneos

    Before receiving Jynneos, tell the doctor about all other vaccines you have recently received.

    Also tell the doctor if you have recently received drugs or treatments that can weaken the immune system, including:

  • an oral, nasal, inhaled, or injectable steroid medicine;
  • medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders; or
  • medicines to treat or prevent organ transplant rejection.

    • This list is not complete. Other drugs may interact with Jynneos, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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