Zoster vaccine inactivated

Generic name: Zoster Vaccine (inactivated)
Brand names: Shingrix
Dosage form: intramuscular powder for injection (adjuvanted)
Drug class: Viral vaccines

Usage of Zoster vaccine inactivated

Herpes zoster is caused by the same virus (varicella) that causes chickenpox in children. When this virus becomes active again, it can cause herpes zoster, or shingles. Inactivated zoster vaccine helps prevent shingles.

This vaccine works by exposing you to a small dose of inactive virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.

Inactivated zoster vaccine is used to prevent herpes zoster virus (shingles):

  • in people age 50 and older, including people who previously received a live zoster vaccine (Zostavax); and
  • in people 18 years and older at increased risk of herpes zoster virus (shingles) due to a weak immune system.
  • Inactivated zoster vaccine will not treat chickenpox, shingles, or nerve pain caused by shingles (post-herpetic neuralgia).

    Inactivated zoster vaccine may also be used for purposes not listed in this medication guide.

    Zoster vaccine inactivated side effects

    You should not receive the second shot if you had a life-threatening allergic reaction after the first shot.

    Keep track of any and all side effects you have after receiving inactivated zoster vaccine. When you receive the second shot, tell the doctor if the first shot caused any side effects.

    Becoming infected with shingles is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

    Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Some people receiving this vaccine had nervous system problems within 42 days after receiving this vaccine, but the risk of this side effect is very low. Seek medical attention right away if you have:

  • weakness or tingling;
  • trouble speaking or swallowing;
  • problems with balance or eye movement; or
  • loss of bladder or bowel control.
  • Call your doctor at once if you have a high fever.

    Common side effects include:

  • headache, muscle pain;
  • feeling tired;
  • stomach pain, nausea, vomiting, diarrhea;
  • fever, shivering; or
  • pain, redness, or swelling where the shot was given.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

    Before taking Zoster vaccine inactivated

    You should not receive this vaccine if you have ever had a life-threatening allergic reaction to inactivated zoster virus vaccine.

    Tell your doctor if:

  • you have ever had an allergic reaction to any vaccine; or
  • you have fainted after receiving an injection.
  • Tell your doctor if you are pregnant or breastfeeding.

    Relate drugs

    How to use Zoster vaccine inactivated

    Usual Adult Dose for Varicella-Zoster -- Prophylaxis:

    0.5 mL intramuscularly -Administer two doses, with the second dose given 2 to 6 months after the first doseComments:-This drug is not indicated for prevention of primary varicella infection (chickenpox).Uses: Prevention of herpes zoster (shingles) in:-Adults aged 50 years and older-Adults aged 18 years and older at increased risk of herpes zoster (HZ) due to immunodeficiency or immunosuppression from disease or therapy


    You should not receive the second shot if you had a life-threatening allergic reaction after the first shot.

    What other drugs will affect Zoster vaccine inactivated

    Other drugs may affect inactivated zoster vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.


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